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Pitstop 2
CAS No. 1419093-54-1
Pitstop 2 ( Pitstop-2;Pitstop2 )
产品货号. M11752 CAS No. 1419093-54-1
A small molecule inhibitor of clathrin terminal domain and inhibits clathrin-mediated endocytosis.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Pitstop 2
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A small molecule inhibitor of clathrin terminal domain and inhibits clathrin-mediated endocytosis.
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产品描述A small molecule inhibitor of clathrin terminal domain and inhibits clathrin-mediated endocytosis; inhibits endocytosis of transferrin receptor, a CDE cargo protein, but not affect endocytosis of shiga toxin; traps HeLa cells in metaphase through loss of mitotic spindle integrity and activation of the spindle assembly checkpoint, a useful tool for investigating clathrin spindle dynamics.
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同义词Pitstop-2;Pitstop2
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通路Others
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靶点Clathrin
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受体Clathrin
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研究领域——
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适应症——
化学信息
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CAS Number1419093-54-1
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分子量473.36
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分子式C20H13BrN2O3S2
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纯度>98% (HPLC)
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溶解度——
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SMILESC1=CC=C2C(=C1)C=CC=C2S(=O)(=O)N=C3NC(=O)C(=CC4=CC=C(C=C4)Br)S3
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化学全称(Z)-N-(5-(4-bromobenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)naphthalene-1-sulfonamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Dutta D, et al. PLoS One. 2012;7(9):e45799.
2. Smith CM, et al. Mol Cancer. 2013 Jan 17;12:4.
3. Liashkovich I, et al. Sci Rep. 2015 May 6;5:9994.
4. Willox AK, et al. Biol Open. 2014 Apr 4;3(5):326-31.
2. Smith CM, et al. Mol Cancer. 2013 Jan 17;12:4.
3. Liashkovich I, et al. Sci Rep. 2015 May 6;5:9994.
4. Willox AK, et al. Biol Open. 2014 Apr 4;3(5):326-31.
产品手册
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Pitstop 2 (b)
A small molecule inhibitor of clathrin terminal domain and inhibits clathrin-mediated endocytosis.
